What is BioPerine® and How Does it Enhance Bioavailability of Drugs?
Did you see this spectacular lil’ word BioPerine on your supplement panel and you’re Googling your lil’ heart out until you know what it is? Good for you, curious soul.
Knowledge is power.
BioPerine is a patented extract obtained from black pepper fruits. Piperine is another name for it, and it is a bioavailability enhancer.
Whoa, already with the big words? OK, OK—its black pepper and it improves absorption of supplements and drugs you take.
So, if you see it in your pre-workout or your weight loss drug, it’s in there to make it more ‘effective’.
How BioPerine Works
BioPerine, or piperine, acts like that little sister that gets into between you and your BFF. Sure, it’s just like that, but it does it with enzymes that break down ingredients in your weight loss drugs or supplements.
Pretend you and your BFF are tossing a ball back and forth and each time one of you catches it, your body digests an ingredient from your supplement. Now, say the little brat steps in between you two and catches that ball—the ingredient that would have been broken down, is now hanging around longer to be absorbed intact, rather than biodegraded and metabolized.
So piperine, or BioPerine, interferes with oxidative and metabolic processes. It also stimulates absorption of ingredients and drugs by triggering amino acid transporters in your belly, makes it harder for drugs to be eliminated and ‘wasted’ in your system, and inhibits the production of intestinal acids that would waste your ingredients. As such, it allows your body to absorb and use more of the ingredients than it would without it.
BioPerine, or black pepper, varies in how it works with each drug or ingredient because each drug or ingredient is metabolized differently by your body.
To put it simply, pepper makes drugs and ingredients more effective.
Why is that necessary? Because the body does not absorb all drugs and nutrients effectively or wholly.
BioPerine (Black Pepper) Increases Benefits of Drugs and Reduces Dosage
A drug’s bioavailability refers to the percentage of it that is ultimately absorbed by the body. A drug with low bioavailability does not have as much of an effect if you were to take that drug, say, intravenously. This is due to the enzymes, metabolic processes and digestion progressions of the body when drugs are taken orally.
Drugs with low bioavailability aren’t as effective. These drugs are prescribed at higher doses as a result, in order to attain the benefits they offer.
Higher dosing comes with more potentially unsafe side effects.
Black pepper, or piperine, is recognized as a bioavailability enhancer by the white lab coat society, aka scientific community, since 1979.
There is so much science behind it, too.
Black Pepper Bioavailability Studies
BioPerine studies show it can improve nutrient absorption by at least 30%.
Piperine increases the bioavailability of various drugs ranging from 30 percent to 2000 percent.
To demonstrate how it varies, research shows that piperine increases curcumin bioavailability by nearly ten-fold.
There are tons of studies out there just like that. Just keep letting your curious mind Google and you’ll be busy for days.
In summary increasing bioavailability of drugs and/or nutrients with black pepper, aka piperine / BioPerine increases its effectiveness and decreases dosage amounts.
Speaking of doses, you probably want to know how much BioPerine you need to make your supplement or weight loss drugs more effective. It’s around 15-20 mg a day.
Start Supplementing with BioPerine or Black Pepper and Improve Absorption
So, there you have it. You increased the bioavailability of your IQ by getting your brain buff on this BioPerine blog. Now, go think about increasing the bioavailability of your weight loss drugs or supplements with some black pepper. If your supplement or weight loss drugs don’t have black pepper in them, you should buy elsewhere. Don’t waste your money and time and not get results. Get supplements with BioPerine here.